Zinc Supplement on Tissue Arsenic Concentration in Rats

To examine the effect of zinc in the removal of accumulated arsenic from different tissues Oiver, kidneys, spleen and lungs), rats were initially allowed to drink high concentration (400 ~gIday) of arsenic for two months followed by a period of cessation (one month). Administration of zinc (2 mglkg/day) during the third month in arsenic-treated and non-treated groups were compared. In arsenic-treated rats, the mean(::!:SD) amounts oftotal arsenic in liver, kidneys, spleen and lungs were 12.3:tO.7, 20.5:!:1.0, 31.4:!:1.0 and 25.6:!:1.1 ~g of tissues respectively.


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