Patients with idiopathic thrombocytopenic pupura (ITP), when under goes any cardiac surgery face an increased risk of postoperative haemorrhagic complications. A 28 years old female patient with idiopathic thrombocytopenic purpura(ITP) and Ventricular septal defect (VSD) with pulmonary stenosis (PS) was operated. We treated her with oral steroid for three weeks immediately before surgery. During surgery under extracorporeal circulation bleeding was controlled meticulously and she was administered methyl prednisolone, injection hydrocortisone, fresh frozen plasma, platelets and whole blood. Steroid was continued postoperatively for two weeks.