Sucralfate in the Prevention of Duodenal Ulcer Relapse and Factors Influencing the Relapse Rate

Forty three subiects with DU conlirmed at endoscopy and healed alter eight weeks of sucralfate therapy were subjected to a randomized double-blind controlled trial lor six months. Tweniy one subiects received sucraltale (‘l g one hour before breakfast and dinner). Twenty two subiects received placebo. Symptoms were evaluated every month. The subjects were endoscoped at the end of the trial or earlier in case symptoms recurred. Sucralfatewas tound to be significantly more effective than placebo (6/21 vs. ‘17122, p<0.005) in prevenling DU relapse…

 

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