Single Photon Emission Computed Tomography (SPECT) was introduced in the early 1980s as an instrument for the evaluation of Regional Cerebral Perfusion (RCP) and receptor density studies. For the performance of SPECT, a flow tracer or a receptor – binding substance is tagged with rationuclide and injected intravenously into the patient. The radiotracer is assumed to accumulate in different areas of the brain, proportionately to the rate of delivery of nutrients to that volume of brain tissue.