Though the health situation of Bangladesh has improved substantially over the years, the low birth weight (LBW) rate is still pretty high. The principal focus of this study was to ascertain the significant determinants for LBW. One hundred and eight LBW babies were compared with 357 normal birth weight babies. Out of 20 possible risk variables analyzed, 9 were found significant when studied separately. Mother’s age, education, occupation, yearly income, gravid status, gestational age at first visit, number of antenatal care visit attended, quality of antenatal care received and pre-delivery body mass index had significantly associated with the incidence of LBW.