Bangladesh Medical Research Council (BMRC)
The objective of the present study was to see the prevalence of anticardiolipin antibody (ACA) in Bangladeshi patients (35) with recurrent pregnancy loss. Thirty-seven women with normal pregnancy were included as control. Serum levels (mean ± SD) of ACA (u/mL) was significantly higher, whereas ANA (Ab-index) and anti-dsDNA (Ab-index) were similar in cases compared to controls (Cases vs Controls J ACA: 31.8 ± 24.3 vs 10.5 ± 3.4, p<0.001; ANA: 1.07 ± 0.34 vs 0.92 ± 0.15, p>0.5; AdsDNA: 0.53 ± 0.16 vs 0.52 ± 0.18, p>0.5). The cases positive for ACA, ANA and anti-dsDNA were 37.1% (p<0.001), 20% (p>0.05) and 2.8% (p>0.1) respectively. Among the seropositive cases 4/35 (11.4%) and 4/13 (30.8%) were positive for both ACA and ANA.