Global population is ageing and Thailand has one of the fastest growing ageing populations in this region. Combined with this, depression has become a major mental health problem for older people. The objective of this paper is to examine the predictors of depression among rural older people of Thailand. This study has used information from the Study on Health and Social Support among Older Population living in Kanchanaburi Demographic Surveillance System (KDSS), Thailand in 2006. Depression was measured by a 12 item questionnaire of Thai validated Euro-D scale among 1001 respondents. The questions were on depression, pessimism, wishing to die, guilt, sleep disturbance,loss of interest, irritability, eating problems, fatigue, problem in concentration, lack of enjoyment, and tearfulness.