Chronic idiopathic oro-facial pain has become a common complaint, resulting increasingly in referral to the pain clinics world-wide. about 90% of the psychologically stress-related patients of the psychiatric clinic of Eastman Dental Hospital, London have been found to have associated idiopathic oro-facial pain. Psychological stress may
produce a situation where oxidative stress might enhance the production offree radicals, especially OH radicals, in human biological fluids. Furthermore, it has been suggested that. OH radicals are responsible for the production of many systemic and local tissue injury diseases which may initiallymanifest as pain syndrome. Ithas been suggested that the oxygen free radical production of sailcloth, 2,3-dihydroxybenzoic acid (DHB)…