MODIFICATION OF PH A-STIMULATED LYMPHOCYTE ACTIVATION BY ETHYL ALCOHOL IN VITRO.

Phytohaemagglutinin (PHA) stimulated tritiated thymidine incorporation (lymphocyte activation) by guinea-pig lymph node lymphocytes was inhibited by ethyl alcohol. The inhibitory effect with higher doses is due partly to
cytotoxicity. This modification of the classical lymphocyte activation test by solvent should be taken into account when testing the effects of drugs on such system…

 

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