Islet Cell Autoantibody and Glutamic Acid Decarboxylase-65 Autoantibody in Young Diabetic patients in a General Hospital of Dhaka City

Background: Immune mediated destruction of pancreatic beta cell in type-I diabetes is well established but its’ role in young type-2 diabetic patients is still not conclusive. These young diabetic patients pass through several stages where they do not need insulin but found to have serum autoantibody against islets cell and even become dependent on insulin for survival in course of time. This study aims to find the presence of islets cell auto-antibodies (ICA) and autoantibody to glutamic acid decarboxylase-65 (GAD65) in non-insulin requiring young diabetic patients of Bangladesh.


Download PDF