Higher prevalence of Cytomegalovius pp65 antigenemia associated with lower CD4+ T lymphocyte count

Sixty seven immunocompromised patients were studied prospectively to observe the association of Cytomegalovirus (CMV) pp65 antigenemia with CD4+ T-lymphocyte count, a marker of cellular immunity. This study was conducted in three different groups of immunocompromised patients including HIV infected patients, patients with haematological malignancy and kidney transplanted patients. Result of the study indicate that proportion of severely
immunocompromised patients having lower cellular immunity (≤200/µl) in all the three groups were comparable and ranged from 44% to 50%.


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