Bangladesh Medical Research Council (BMRC)
Combined pills have known adverse effects on liver function. Progesterone based contraceptives are thought to be safer in this reard. The effect of Norplant, a levonorestrelcontraceptive implant, on liver function was evaluated in 149 Bangladeshi women of reproductive age in this study. Liver function tests and ultrasonoraphy of hepato-biliary system were done before and after the implantation. The patients were followed upto two years. There were non-significant transient rise of serum bilirubin and slight enlargement of liver durin:.: the first year. There was no significant change in the levels of AST, ALl’, alkaline phosphatase, total protein, albumin-globulin ratio and prothrombin time. The results suggest that Norplant has no adverse effect on liver function…