The hypoglycaemic effect of garlic oil was studied in alloxan and streptozotocin induced -diabetes in guineapigs. The results were compared with a known hypoglycaemic agent tolbutamide. The biochemical changes were correlated with histological changes found in the pancreas of these differently treated animals. Biochemical findings showed
control of diabetes and microscopic findings showed definite evidence of regeneration of beta cells of islets of Langerhans when treated with garlic and tolbutamide. The liver showed more deposition of gl)cogen in both the groups. It is concluded tha…