Dissecting the Contradictory Findings of Angiotensin Converting Enzyme Genetic Polymorphism with Blood Pressure and Hypertension

The studies on the association of deletion/insertion (DIl) polymorphism of angiotensin converting enzyme (ACE) gene with blood pressure and hypertension reported contradictory results. We review the articles that considered blood pressure or hypertension as the main outcome measure to have an overview of the situation. There is heterogeneity of allele frequencies of ACE locus among ethnic groups. In descending order ofD allele frequencies

 

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