Comparative study of efficacy of brush cytology and transthoracic fine needle aspiration cytology in the diagnosis of bronchogenic carcinoma

For long time, bronchoscopic biopsy for histopathology remains the standard in the diagnosis of bronchogenic carcinoma 1-3. The diagnostic yield from biopsy of bronchoscopically visible tumors, occupying the lumen of bronchus is over 90%3. The yield from the bronchoscopically visible but deep seated or intramural tumor is 50 60%3 . In cases of peripheral tumors, the diagnostic yield is much lower. The process usually fails in small peripheral lesions, in the lesions where the bronchi become fibrosed or narrowed, so that the bronchoscope could not reach the site of the lesion 3 . Bronchial cytobrushing, an ancilliary process done during bronchoscopy, yields better results. Bronchial cytobrushing could be done from area of suspicion, having chance of uncertain biopsy 3.


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