Auto-analyzer based screening of microcytic hypochromic ratio to differentiate thalassaemia and non thalassemic microcytosis

This cross sectional analytic study by auto analyzer, performing M/H ratio, helps as a screening tool for thalassaemia trait in Bangladeshi population. Among total of 150 subjects, 50 known obligate carrier of beta-thalassaemia trait and 100 patients with hypochromia and microcytosis were included. In our study, the sensitivity, predictive value and diagnostic accuracy of the M/H ratio for the beta thalassaemia trait were 96%, 90.4% and 90.4%. Thus M/H ratio is an easy, reliable and sensitive index for massscreening of beta-thalassaemia population where iron deficiency anemia is also prevalent.

Download PDF